That is the question!
It is common, for some people, to self diagnose after reading a short
list of symptoms. To those individuals,
knowing that weakness, fatigue, constipation and loss of appetite were symptoms
of B12 deficiency would have them consuming mass quantities of the supplement. However, there are many causes for these
symptoms of which B12 deficiency is only one.
We should look at symptoms as mere guideposts on the journey to an
accurate diagnosis. Other possible
causes could be; hyperparathyroidism, hypopituitarism and Addison's disease. The mere sound of these names may strike fear
in the heart of the self diagnostician, therefore, one may be inclined to treat
with B12 in the hope that a subsequent reduction in symptoms would preclude the
more scary diagnosis.
So let's venture further down the symptom trail in an effort
to support a diagnosis of B12 deficiency.
In addition to the above symptoms one would also expect to see, numbness
in the hands and feet, loss of balance, memory issues, depression, confusion,
and soreness of the oral cavity. This
list, for the most part, is just as subjective as the first, so anyone looking
to convince themselves of a deficiency has a little more work to do.
To make an objective diagnosis we should look for more
objective measures. One tell tale sign
of later stage B12 deficiency is the development
of megaloblastic enemia, a condition of enlarged red blood cells. However, most individuals would like to know
before it gets to that point. Earlier
detection can be determined by measuring for elevated homocysteine or
methylmalonic acid in the blood which rise with B12 deficiency. This method is even more accurate than
measuring blood B12 concentrations itself, due to the fact that intracellular
B12 can be much higher than blood levels.
So let's now assume we have run the tests and we know for
certain that B12 levels are low. Does
this mean that we can merely increase the intake though diet and
supplementation. In order for B12 to be
absorbed into the body it must first be removed from the protein that caries it
in our food. This process is carried out
by the hydrochloric acid in the stomach.
Then it must attach to a different protein, excreted from the stomach
lining, called intrinsic factor which will facilitate it's absorption in the
intestines. If either of these steps is
compromised then the amount of B12 absorption will be limited.
For individuals, who self medicate with antacids for
digestive issues such as ulcers, heart burn or indigestion, there is a
reduction in stomach acid that does not allow the initial protein to be removed
so the B12 is not available for binding
to the intrinsic factor. Additionally,
people with pernicious anemia lack the ability to produce intrinsic factor thereby eliminating the handle that
facilitates absorption. Even with normal intrinsic factor production,
there is a finite amount of it produced and therefore a natural limit to the amount
of B12 that may be absorbed. It is for these reasons that if one is
severely deficient in B12 the best course of treatment is intravenous B12
injections.
There has been some indicators that B12 can be absorbed
through mucous membranes such as those located in the oral cavity. To facilitate absorption it is said that
placing a B12 tablet under the tongue until it dissolves will increase the
amount absorbed.
Ultimately, this is one case where verifying a need can save
money in the long run.
Image courtesy of artemisphoto / FreeDigitalPhotos.net
For more information about Dr White and Action Chiropractic go to: www.DanburyActionChiropractic.com